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เซอร์ปิน บี8 (อังกฤษ: Serpin B8 หรือ SERPINB8) เป็นโปรตีนของมนุษย์ และเป็นโปรตีนสมาชิกลำดับที่ 8 ในเคลดบีของเซอร์ปิน (Serpin family B member 8) ถูกถอดรหัสได้โดยยีน SERPINB8 บน
| SERPINB8 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SERPINB8, CAP2, PI8, serpin family B member 8, PSS5, PI-8, HMSD, HSMD-v, C18orf53 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | : 601697 : 894657 : 74445 : SERPINB8 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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ดูเพิ่ม
อ้างอิง
- GRCh38: Ensembl release 89: ENSG00000166401 – , May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000026315 – , May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem. 270 (50): 29854–61. doi:10.1074/jbc.270.50.29854. PMID 8530382.
- Bartuski AJ, Kamachi Y, Schick C, Overhauser J, Silverman GA (Nov 1997). "Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3". Genomics. 43 (3): 321–8. doi:10.1006/geno.1997.4827. PMID 9268635.
- "Entrez Gene: SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8".
แหล่งข้อมูลอื่น
- Hubberstey A, Yu G, Loewith R, และคณะ (1997). "Mammalian CAP interacts with CAP, CAP2, and actin". J. Cell. Biochem. 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950.
- Dahlen JR, Foster DC, Kisiel W (1998). "Expression, purification, and inhibitory properties of human proteinase inhibitor". Biochemistry. 36 (48): 14874–82. doi:10.1021/bi970977p. PMID 9402754.
- Reddy PH, Stockburger E, Gillevet P, Tagle DA (1998). "Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method". Genomics. 46 (2): 174–82. doi:10.1006/geno.1997.5044. PMID 9417904.
- Dahlen JR, Jean F, Thomas G, และคณะ (1998). "Inhibition of soluble recombinant furin by human proteinase inhibitor 8". J. Biol. Chem. 273 (4): 1851–4. doi:10.1074/jbc.273.4.1851. PMID 9442015.
- Strik MC, Bladergroen BA, Wouters D, และคณะ (2003). "Distribution of the human intracellular serpin protease inhibitor 8 in human tissues". J. Histochem. Cytochem. 50 (11): 1443–54. doi:10.1177/002215540205001103. PMID 12417609.
- Strausberg RL, Feingold EA, Grouse LH, และคณะ (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hoetelmans RW (2004). "Nuclear partners of Bcl-2: Bax and PML". DNA Cell Biol. 23 (6): 351–4. doi:10.1089/104454904323145236. PMID 15231068.
- Rual JF, Venkatesan K, Hao T, และคณะ (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Leblond J, Laprise MH, Gaudreau S, และคณะ (2006). "The serpin proteinase inhibitor 8: an endogenous furin inhibitor released from human platelets". Thromb. Haemost. 95 (2): 243–52. doi:10.1160/TH05-08-0561. PMID 16493485.
- ฐานข้อมูลออนไลน์ สำหรับเปปทิเดส และสารยับยั้งเปปทิเดส: I04.013[]
- SERPINB8 protein, human ใน สำหรับหัวข้อเนื้อหาทางการแพทย์ (MeSH)
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esxrpin bi8 xngkvs Serpin B8 hrux SERPINB8 epnoprtinkhxngmnusy aelaepnoprtinsmachikladbthi 8 inekhldbikhxngesxrpin Serpin family B member 8 thukthxdrhsidodyyin SERPINB8 bnSERPINB8IdentifiersSERPINB8 CAP2 PI8 serpin family B member 8 PSS5 PI 8 HMSD HSMD v C18orf53External IDs 601697 894657 74445 SERPINB8Gene location Human Chr 18q22 1Start63 970 029 bpEnd64 019 779 bpGene location Chr Chromosome 1 mouse 1 1 E2 1Start107 517 736 bpEnd107 538 214 bpRNA expression patternBgeeHuman ortholog Top expressed inskin of leg skin of abdomen gingival epithelium Descending thoracic aorta tibial arteriesTop expressed inlumbar spinal ganglion skin of external ear skin of back conjunctival fornix skin of abdomen stroma of bone marrow cervixMore reference expression dataBioGPSMore reference expression dataMolecular functionpeptidase inhibitor activity karcbkboprtin serine type endopeptidase inhibitor activityCellular componentisothphlasum isotsxl exkososmchnidphaynxkesll phaynxkesll sarekhluxbesllthimikhxllaecnepnswnprakxbBiological processnegative regulation of peptidase activity negative regulation of endopeptidase activity epithelial cell cell adhesionSources Amigo QuickGOSpeciesHumanMouse527120725ENSG00000166401ENSMUSG00000026315P50452O08800RefSeq mRNA NM 001031848 NM 001276490 NM 002640 NM 198833 NM 001348367NM 001348368 NM 001348369 NM 001348370 NM 001366198NM 001159748 NM 011459RefSeq protein NP 001027018 NP 001263419 NP 002631 NP 942130 NP 001335296NP 001335297 NP 001335298 NP 001335299 NP 001353127NP 001153220 NP 035589Location UCSC Chr 18 63 97 64 02 MbChr 1 107 52 107 54 MbPubMed searchWikidataView Edit HumanView Edit MouseduephimesxrpinxangxingGRCh38 Ensembl release 89 ENSG00000166401 May 2017 GRCm38 Ensembl release 89 ENSMUSG00000026315 May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Sprecher CA Morgenstern KA Mathewes S Dahlen JR Schrader SK Foster DC Kisiel W Jan 1996 Molecular cloning expression and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors J Biol Chem 270 50 29854 61 doi 10 1074 jbc 270 50 29854 PMID 8530382 Bartuski AJ Kamachi Y Schick C Overhauser J Silverman GA Nov 1997 Cytoplasmic antiproteinase 2 PI8 and bomapin PI10 map to the serpin cluster at 18q21 3 Genomics 43 3 321 8 doi 10 1006 geno 1997 4827 PMID 9268635 Entrez Gene SERPINB8 serpin peptidase inhibitor clade B ovalbumin member 8 aehlngkhxmulxunHubberstey A Yu G Loewith R aelakhna 1997 Mammalian CAP interacts with CAP CAP2 and actin J Cell Biochem 61 3 459 66 doi 10 1002 SICI 1097 4644 19960601 61 3 lt 459 AID JCB13 gt 3 0 CO 2 E PMID 8761950 Dahlen JR Foster DC Kisiel W 1998 Expression purification and inhibitory properties of human proteinase inhibitor Biochemistry 36 48 14874 82 doi 10 1021 bi970977p PMID 9402754 Reddy PH Stockburger E Gillevet P Tagle DA 1998 Mapping and characterization of novel CAG n repeat cDNAs from adult human brain derived by the oligo capture method Genomics 46 2 174 82 doi 10 1006 geno 1997 5044 PMID 9417904 Dahlen JR Jean F Thomas G aelakhna 1998 Inhibition of soluble recombinant furin by human proteinase inhibitor 8 J Biol Chem 273 4 1851 4 doi 10 1074 jbc 273 4 1851 PMID 9442015 Strik MC Bladergroen BA Wouters D aelakhna 2003 Distribution of the human intracellular serpin protease inhibitor 8 in human tissues J Histochem Cytochem 50 11 1443 54 doi 10 1177 002215540205001103 PMID 12417609 Strausberg RL Feingold EA Grouse LH aelakhna 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Hoetelmans RW 2004 Nuclear partners of Bcl 2 Bax and PML DNA Cell Biol 23 6 351 4 doi 10 1089 104454904323145236 PMID 15231068 Rual JF Venkatesan K Hao T aelakhna 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Leblond J Laprise MH Gaudreau S aelakhna 2006 The serpin proteinase inhibitor 8 an endogenous furin inhibitor released from human platelets Thromb Haemost 95 2 243 52 doi 10 1160 TH05 08 0561 PMID 16493485 thankhxmulxxniln sahrbeppthieds aelasarybyngeppthieds I04 013 lingkesiy SERPINB8 protein human in sahrbhwkhxenuxhathangkaraephthy MeSH bthkhwamekiywkhxngkbyinbn niyngepnokhrng khunsamarthchwywikiphiediyidodykarephimetimkhxmul